Lately, I've been more intrigued by short first lines than their long counterparts.  Short first lines seem to pack a swifter kick to the crotch then a more wordy first line.  So have a look at this one:
Now I believe they will leave me alone.
What? Who will leave you alone?  And Booooom, you're into the novel.  This first line comes from one of my all time favorites: The Angle of Repose by Wallace Stegner.  The rest of the novel is perhaps one of the more artfully configured works of literature that I have ever laid eyes upon . . . and it has a good first line to boot!